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Lisa Lapidus

Department of Physics and Astronomy

BPS 4227 | web site |

  • Protein folding and aggregation on ns to ms time scales
  • Laser spectroscopy and microfluidics
  • Dynamic reconfiguration in unfolded proteins

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Recent Publications

Combined Force Ramp and Equilibrium High-Resolution Investigations Reveal Multipath Heterogeneous Unfolding of Protein G.
Izadi D, Chen Y, Whitmore ML, Slivka JD, Ching K, Lapidus LJ, Comstock MJ.
J Phys Chem B (2018) Dec 13; 122(49):11155-11165.

Intramolecular Diffusion in α-Synuclein: It Depends on How You Measure It.
Woodard J, Srivastava KR, Rahamim G, Grupi A, Hogan S, Witalka DJ, Nawrocki G, Haas E, Feig M, Lapidus LJ.
Biophys J (2018) Oct 2; 115(7):1190-1199.

Single molecule force spectroscopy at high data acquisition: A Bayesian nonparametric analysis
Sgouralis I, Whitmore M, Lapidus L, Comstock MJ, Pressé S.
J. Chem. Phys. (2018) Jan 9; 148:123320

Fluorescent Probe DCVJ Shows High Sensitivity for Characterization of Amyloid β-Peptide Early in the Lag Phase.
Nagarajan S, Lapidus LJ.
Chembiochem (2017) Nov 16; 18(22):2205-2211.

Protein unfolding mechanisms and their effects on folding experiments.
Lapidus LJ.
F1000Res (2017) Sep 22.

Enzyme-free electrochemical immunosensor based on methylene blue and the electro-oxidation of hydrazine on Pt nanoparticles.
Dutta G, Nagarajan S, Lapidus LJ, Lillehoj PB.
Biosens Bioelectron (2017) Jun 15; 92:372-377.

Prion protein dynamics before aggregation.
Srivastava KR, Lapidus LJ.
Proc Natl Acad Sci U S A (2017) Apr 4; 114(14):3572-3577.

Complete Procedure for Fabrication of a Fused Silica Ultrarapid Microfluidic Mixer Used in Biophysical Measurements
Izadi D, Nguyen T, Lapidus LJ.
Micromachines (2017) Jan 7; 8(1):16