- Cryo-EM studies of viruses and bacteriophages
- Virus assembly and infection mechanism
- dsDNA-containing bacteriophages
The phage L capsid decoration protein has a novel OB-fold and an unusual capsid binding strategy.
Newcomer RL, Schrad JR, Gilcrease EB, Casjens SR, Feig M, Teschke CM, Alexandrescu AT, Parent KN.
Elife (2019) Apr 4; .
Genes affecting progression of bacteriophage P22 infection in Salmonella identified by transposon and single gene deletion screens.
Bohm K, Porwollik S, Chu W, Dover JA, Gilcrease EB, Casjens SR, McClelland M, Parent KN.
Mol Microbiol (2018) May; 108(3):288-305.
Shigella Phages Isolated during a Dysentery Outbreak Reveal Uncommon Structures and Broad Species Diversity.
Doore SM, Schrad JR, Dean WF, Dover JA, Parent KN.
J Virol (2018) Apr 15; 92:(8).
Breaking Symmetry in Viral Icosahedral Capsids as Seen through the Lenses of X-ray Crystallography and Cryo-Electron Microscopy.
Parent KN, Schrad JR, Cingolani G.
Viruses (2018) Feb 7; 10:(2).
Microscopic Characterization of the Brazilian Giant Samba Virus.
Schrad JR, Young EJ, Abrahão JS, Cortines JR, Parent KN.
Viruses (2017) Feb 14; 9:(2).
Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Lokareddy RK, Sankhala RS, Roy A, Afonine PV, Motwani T, Teschke CM, Parent KN, Cingolani G.
Nat Commun (2017) Jan 30; 8:14310.