2019 Cryo-EM Symposium


Molecular Biophysics Symposium in Honor of the Grand Opening of the MSU Cryo-EM Core Facility

Friday October 4th and Saturday October 5th, 2019

To inaugurate the new Cryo-EM facility at Michigan State, we are hosting a symposium to highlight cutting edge research in molecular biophysics. We will feature invited talks, student posters and a tour of the new cryo-EM facility. Registration is free but required. To submit an abstract for a poster (template), please email biophysics@pa.msu.edu. You can contact Lisa Lapidus for further information.

  • Talks and meals will be in the Radiology building
  • Poster sessions will be in the cryo-EM facility in the Engineering Research Complex
  • Map
  • Program (PDF)

Registration for 2019 is closed.


Program

Friday, October 4

8:00-8:30  Registration/breakfast – Radiology Atrium

8:30-8:35 Acknowledgements – Kristin Parent

8:35-8:45  Introduction - Phil Duxbuy – Radiology Auditorium

8:45-9:00 Introduction - Doug Gage

9:00-9:45 James Conway - Resolving protein structure at high resolution by cryo-electron microscopy - from viruses to crystals

9:45-10:30 Aaron Frank - Data-Driven Solutions to Challenges in Biophysics

10:30 Coffee Break

10:45-11:30 Vinny Manohoran- Watching individual RNA viruses self-assemble

11:30-11:50 Jens Schmidt - Mechanism of processive telomerase catalysis revealed by optical tweezers

11:50-1:00 Lunch – Radiology Atrium

1:15-4:00 Poster session and Cryo-EM Facility Tour –

Saturday, October 5

8:00-9:00 Breakfast

9:00-9:45 Tom Walz - Electron Microscopy Approaches to Studying Lipid-Protein Interactions

9:45-10:30 Yann Chemla - Probing nature’s nano-machines with single-molecule techniques

10:30-10:50 coffee break

10:50-11:10 Dipali Sashital - Memory Formation by the Cas4-Cas1-Cas2 Complex During CRISPR Adaptation

11:10-11:55 Nils Walter - The RNA Nanomachines of Gene Expression Dissected at the Single Molecule Level

11:55- 12:15 Susan Hafenstein- Transferrin receptor binds virus capsids with dynamic motion - receptor and virus rock and roll

12:15-1:45 Lunch

1:45-2:30 Mark Foster - Population Shifts from Allosteric Coupling of RNA and Tryptophan in the Gene-Regulating Ring-Shaped Protein TRAP

2:30-2:50 Kelly Kim - Characterization of membrane proteins using Cryo-EM: a story of insect olfactory receptor Orco

2:50 – 3:35 Liz Kellogg - Cryo-EM structure of the P element transposase strand-transfer complex

3:35 – Closing remarks – Lisa Lapidus


Speakers

Aaron Frank

University of Michigan
Data-Driven Solutions to Challenges in Biophysics

Yann Chemla

University of Illinois at Urbana-Champaign

Vinothan N. Manoharan

Harvard University
Watching individual RNA viruses self-assemble

Nils Walter

University of Michigan
The RNA Nanomachines of Gene Expression Dissected at the Single Molecule Level

Mark Foster

Ohio State University
Population Shifts from Allosteric Coupling of RNA and Tryptophan in the Gene-Regulating Ring-Shaped Protein TRAP

James Conway

University of Pittsburgh
Resolving protein structure at high resolution by cryo-electron microscopy - from viruses to crystals

Liz Kellogg

Cornell University
Cryo-EM structure of the P element transposase strand-transfer complex

Tom Walz

Rockefeller University
Electron Microscopy Approaches to Studying Lipid-Protein Interactions